The Science Behind AbinoNutra®

Clinically validated in humans.

AbinoNutra® NR/NMN, the nutrient that supports healthy aging by enhance your NAD+

AbinoNutra is a U.S.-based longevity nutrition brand under Abinopharm, Inc., founded in 2020 and headquartered in Connecticut.

Focused on clinically studied NMN and NR, AbinoNutra integrates human research, cGMP-certified manufacturing, and rigorous quality standards to deliver affordable, science-backed NAD⁺ support.

Through transparent sourcing, compliant production, and evidence-based formulation, the brand is committed to making high-quality longevity science accessible to everyday consumers worldwide.

The foundation of your cellular energy

The foundation of your cellular energy

Every cell in your body depends on NAD+ (nicotinamide adenine dinucleotide) to function properly. This coenzyme is essential for helping convert the food you eat into ATP—the energy currency that powers all cellular activities. Without adequate NAD+, your cells can't meet their energy demands.

NAD+ serves two critical functions in your body

NAD+ serves two critical functions in your body

Scientists have identified two primary ways this molecule supports cellular health, both of which become increasingly important as we age.

Energy Production

NAD+ facilitates cellular energy creation through redox reactions, cycling between its oxidized form (NAD+) and reduced form (NADH). This process is essential for the three major metabolic pathways that produce ATP: glycolysis breaks down glucose, the citric acid cycle (also known as the Krebs cycle) processes metabolic intermediates, and fatty acid oxidation breaks down fats—all generating the ATP that fuels every cellular process.

Cellular Maintenance and Repair

NAD+ also activates sirtuins—specialized enzymes that help regulate your body's cellular maintenance system. Sirtuins require NAD+ to regulate gene expression, support cellular cleanup processes (autophagy), maintain circadian rhythms, repair DNA, and coordinate stress responses.

The challenge: NAD+ declines over time

The challenge: NAD+ declines over time

Your body obtains NAD+ building blocks from dietary sources like tryptophan and niacin (vitamin B3), and maintains a recycling system called the salvage pathway to reuse NAD+ components. However, these natural mechanisms may not produce sufficient levels to meet your cells' increasing energy demands in tissues, such as in muscle, brain and heart, especially as you age.

Age-related NAD+ decline follows a predictable pattern

Age-related NAD+ decline follows a predictable pattern

Research shows that NAD+ deficiency develops through three interconnected factors that intensify over time and contribute to recognized hallmarks of aging:

• Decreased cellular NAD+ synthesis
• Increased cellular NAD+ consumption
• Consistent exposure to metabolic stressors

High-energy organs experience the most significant impact

High-energy organs experience the most significant impact

Tissues with the greatest metabolic demands are likely to be most affected by NAD+ depletion, offering a potential explanation as to why certain age-related changes become noticeable first:


• Brain Health
• Cardiovascular Health
• Muscle Health

Effective NAD+ support requires the right approach

Effective NAD+ support requires the right approach

While your body's natural NAD+ production and recycling systems work continuously, they may become increasingly inadequate with age and metabolic stress. Not all NAD+ precursors are created equal—your cells have specific pathways and limitations for converting these molecules into usable NAD+.

β-Nicotinamide Mononucleotide (NMN)/Nicotinamide riboside (NR) offers a uniquely efficient route to NAD+ replenishment

Unlike direct NAD+ supplementation, which faces absorption challenges due to the molecule's size and instability, this targeted approach to restoring NAD+ levels can help bridge the critical energy gap, leading to:


• Supported cellular energy production
• Maintenance of cellular repair
• Supported metabolic efficiency

Pharmaceutical Depth Behind Every Formula

AbinoNutra is backed by Abinopharm’s expertise across active pharmaceutical ingredients, compounded medicines, generics, biosimilars, NDA programs, regulatory filings, and healthy-longevity research.

100+

Years of combined biotech, pharmaceutical, and healthcare experience.

80+

*API programs across commercial, DMF-filed, and R&D stages.

10+

Generic and biosimilar drug products in the U.S. approval and filing pipeline.

4+

Pharmaceutical pathways spanning compounding, generics, biosimilars, and NDA development.

Our golden standard

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Clinically studied NAD⁺ support, backed by human research

AbinoNutra® is built around clinically studied NAD⁺ support, including published human NMN research and broader human evidence on NAD⁺ precursors. These studies help ground the formula story in measurable human data, including NAD⁺ response, tolerability, and healthy-aging related outcomes.

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Human NMN trial in 80 healthy middle-aged adults

A randomized, multicenter, double-blind, placebo-controlled GeroScience study evaluating 300 mg, 600 mg, and 900 mg NMN over 60 days.

Personalized NAD⁺ response after NMN supplementation

A post-hoc analysis exploring individual NAD⁺ response patterns after NMN supplementation.

NAD⁺ levels and laboratory parameters after NMN

A GeroScience post-hoc analysis examining associations between blood NAD⁺ levels and laboratory markers.

Award-recognized NMN clinical publication

The original NMN study received Third Prize in the 2024 GeroScience Outstanding Original Research Paper Award.

NMN and post-exercise inflammation pilot study

A human pilot study using AbinoNutra® NMN to explore post-exercise inflammation and skeletal muscle recovery.

Human NR evidence for NAD⁺ metabolism

Published human research showing nicotinamide riboside can elevate NAD⁺ metabolism and is generally well tolerated in healthy adults.

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Pharmaceutical-grade quality from ingredient to capsule

AbinoNutra® pairs clinically researched ingredients with documented safety, regulatory, and manufacturing quality signals. From NAD⁺ precursors to cellular-protection nutrients, its ingredient platform is supported by external safety reviews, FDA GRAS records, and industry-published quality documentation.

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FDA GRAS notice for nicotinamide riboside chloride

FDA GRN 635 documents nicotinamide riboside chloride as a source of vitamin B3.

EFSA safety opinion on nicotinamide riboside

EFSA published safety opinions on nicotinamide riboside chloride as a novel food and source of niacin.

FDA GRAS record for Dr.Ergo® L-Ergothioneine

FDA GRN 1191 lists Dr.Ergo® L-Ergothioneine, with FDA’s public “no questions” response letter.

Independent GRAS review for Dr.Ergo® Ergothioneine

SGS Nutrasource reported that an independent expert panel agreed with the GRAS conclusion for Dr.Ergo® L-Ergothioneine.

Industry coverage of Dr.Ergo® FDA GRAS milestone

Nutraceutical Business Review covered the FDA GRAS milestone for Dr.Ergo® Ergothioneine.

Published quality claims for Dr.Ergo® production

External PR coverage reports cGMP guidance, NSF GMP, HACCP, HALAL, and >99.9% purity claims for Dr.Ergo® L-Ergothioneine.

External white paper coverage on NMN quality and safety

BioSpace coverage summarizes AbinoNutra® NMN’s white paper focus on quality standards, safety profile, and human clinical evidence.